Page Venture Gallery Venture Gallery View startups founded from across the University of Chicago ecosystem in a range of industries. Welcome to the Venture Gallery! The Polsky Center provides “first look” and early...
Technology PMO-Based RNA-Degrading Chimeras For Targeted Degradation Of α-Synuclein mRNA In Neurodegenerative Diseases Phosphorodiamidate morpholino oligomer (PMO)-based RNA-degrading chimeras reduce α-synuclein protein by degrading its messenger RNA preventing protein aggregation and propagation associated with neurodegenerative diseases. The Unmet Need: More potent and selective…
News Polsky Center Fall 2021 I-Corps Teams Tackle Unmet Medical Needs, Data Transparency, and Other Challenges The Polsky Center’s fall 2021 I-Corps cohort is developing diagnostics, novel therapeutics, innovative devices, new materials, and other technologies across various industries. The Polsky I-Corps program is a 7-week highly-experiential...
News AbbVie Joins UChicago to Talk Oncology Research, Ongoing Collaboration, and Opportunities for Expansion The annual UChicago-AbbVie Research Symposium in August celebrated another successful year of the strategic partnership – bringing together academia and industry to exchange new ideas and drive innovation. The event...
News Commercialization Fellowship Welcome Five New PhD Students to Further Develop Research The Polsky Center for Entrepreneurship and Innovation welcomes five new University of Chicago PhD students to its Commercialization Fellowship program, which offers students the opportunity to create new ventures around promising...
Technology Fatty Acid Nutraceuticals For Enhancing Immune Development In Newborns And T Cell-Based Cancer Therapies Nutraceutical approach using specific fatty acids naturally found in human breast milk incorporated into infant formula enhancing immune defense in both neonates and adults The Unmet Need: Solutions for effectively…
Technology Dietary Supplement To Enhance Anti-Tumor Immunity A method to utilize trans-vaccenic acid to enhance CD8+ T cell-mediated anti-tumor immunity through an innovated mechanism promoting T cell activation, infiltration, and survival while reducing exhaustion markers The Unmet…
Technology Senolytic Therapeutics To Eliminate Senescent Cells And Enhance Aging And Cancer Treatments Targeted approach to remove aging, disease-related, or chemotherapy/immunotherapy-induced senescent cells while sparing healthy cells The Unmet Need: Approaches to selectively eliminate senescent cells improving aging symptoms without damaging healthy…
Technology Small Molecule Splicing Modulators For Reducing Aggregatable Prion Protein In Prion Diseases First-in-class small molecules to change how the PRNP gene is spliced, reducing harmful prion levels and offering a new treatment approach for prion diseases The Unmet Need: Safe, effective,…
Technology Topical Vitamin B1-Based Immunomodulation For Enhancing Skin Wound Healing And Anti-Tumor Responses Skincare Vitamin B1 functions as a novel immunomodulator that reprograms skin dendritic cell efferocytosis and antigen presenting cell functions, leading to enhanced skin immunity for would healing and anti-tumor purpose…
News Polsky Center I-Corps Teams Test Commercialization Potential of Research The Polsky I-Corps program helps scientists, researchers, and students test the commercial potential of their research and ideas. Supported with funding from the National Science Foundation (NSF) through the Great...
Technology Mesenchymal Stem Cell And Exosome-Based Therapeutics For Restoring Ovarian Function In Premature Ovarian Insufficiency Therapeutic strategy using human mesenchymal stem cells or their exosomes to restore ovarian function and fertility in premature ovarian insufficiency by promoting cell growth, reducing cell death, and enhancing blood…
