News Using Nanotechnology to Deliver ‘Potentially Transformative’ Peptide-Based Therapeutics A physician-scientist, James Labelle is developing therapies that modify the function of the immune system – by examining why, on a molecular level, some pediatric cancers are resistant to treatment....
News Illinois Ignite: Researchers to Showcase Breakthroughs in Healthcare, Computing, and Advanced Manufacturing Illinois Ignite 2020 will feature technologies and startups from the University of Chicago, Northwestern University, University of Illinois Urbana-Champaign, University of Illinois-Chicago, and Illinois Institute of Technology. The virtual showcase...
Technology Nanomaterial Based Intracellular Drug Delivery Of Therapeutic Peptides Intracellular delivery involves introduction of small biomolecules, nucleic acids, proteins, synthetic nanomaterials and drugs into the cell. There is a lot of focus on targeted intracellular delivery for improved therapy…
Technology FOXP3 Stapled Peptides to Deactivate Regulatory T Cells Regulatory T cells (Tregs) modulate immune function by preventing autoreactive T cell responses, including those that would normally target cancer cells. Treg activity can significantly limit the efficacy of immunotherapies…
Technology Hydrocarbon-Stapled Peptides To Inhibit SARS-CoV-2 Viral Infection The SARS-CoV-2 virus spreads by binding its spike protein to the human angiotensin-converting enzyme 2 (hACE2) protein expressed at the cell surface of lungs, arteries, heart, kidney, and intestines. The…
Technology Expanding CAR T Cells Using Venetoclax For Enhanced Cytolytic Activity Against Tumors Expanding CAR T cells with venetoclax enhances their ability to target and kill CD19+ tumor cells, increases their effectiveness, and reduces exhaustion, potentially leading to better treatment outcomes for diffuse…
Page Polsky Council The Polsky Council comprises many of the country’s leading entrepreneurs, venture capitalists, and private equity investors, who provide ongoing guidance and support to the Polsky Center.
News 3 Novel Disease-Fighting Technologies You Should Know About Ahead of BIO 2022 Researchers at the University of Chicago have developed methods to increase the clinical efficacy of immunotherapies, provide long-lasting immune tolerance for autoimmune or transplantation therapy, and treat breast and ovarian...
Technology Type I Interferons For Enhancing Chimeric Antigen Receptor T-Cell Efficacy Method to enhance CAR T-cell efficacy by incorporating low-dose exogenous IFN-α2 into CD19-directed, CD28-costimulated CAR T cells post-transduction during manufacturing boosting cytolytic molecule expression, cytokine secretion, and cytotoxicity while minimizing…
News Monsters of the Midway UChicago licensee NephRx is moving swiftly to bring to market therapeutics for patients with kidney transplants and mucositis. Nephrology professor Gary Toback, MD, PhD (left) developed the therapies that have...
News Booth’s Student Entrepreneurship Awards Honor Budding Leaders in Entrepreneurship, Venture Capital and Private Equity Chicago Booth last month recognized six outstanding MBA students who demonstrated leadership in entrepreneurship, venture capital or private equity during their time at school. The annual Student Entrepreneurship Awards have...
News UChicago Professors and Grad Students Among 2021’s Highly Cited Researchers More than 30 professors and graduate students at the University of Chicago were among Clarivate’s annual list of Highly Cited Researchers. The list, which included University of Chicago President, Paul...
