Technology Prolactin Receptor Antibodies For Targeted Cancer Therapy And Diagnosis Novel antibodies precisely targeting cancer cells by binding to the Prolactin Receptor (PRLR) to diagnose cancer, direct immune cells to destroy tumors, and inhibit cancer growth signals, without affecting healthy…
Technology Computational Framework For Unraveling Single-Cell Transcriptional Dynamics Novel system using statistical topic modeling and a bursty transcriptional model to analyze spliced and unspliced RNA, revealing precise cell state transitions and dynamics in complex biological systems The Unmet…
Technology Integration Of Semiconductor-Based Components And Functionality Into Soft Microfluidics For Cell Lysis And Other Biological Applications This technology delivers precise and scalable cellular content extraction for genomic analyses by integrating semiconductor-based piezoelectric sharp tip arrays into soft microfluidics, enabling efficient mechanical cell lysis, particularly of hard-shelled…
News Meet the Inaugural Alchemist Chicago Cohort Alchemist Accelerator and the University of Chicago’s Polsky Center for Entrepreneurship and Innovation are thrilled to announce the inaugural cohort of Alchemist Chicago. Alchemist Chicago Cohort 1 is made up...
News Life Sciences Community Convenes at Chicago BioCapital Summit in a Showcase of Local Innovation Hosted by the Chicago Biomedical Consortium (CBC), the inaugural Chicago BioCapital Summit this week brought together industry, academia, and investors in a showcase of the latest innovations in the life...
Technology A Neural Network to Quantify in Situ Adaptive Immunity in Autoimmune Disorders Presently, the use of single cell methods such as RNA sequencing can identify rare inflammatory cellular populations that can be used for the diagnosis of autoimmune disorders. However, the scope…
Technology Optogenetic Protein Fusion for Precise And Low-Impact Actin Cytoskeleton Imaging In Cells A light-sensitive version of LifeAct, a peptide used to label actin in cells, to reduce its harmful side effects by controlling its binding through light exposure, improving cell imaging and…
Technology Dietary Supplement To Enhance Anti-Tumor Immunity A method to utilize trans-vaccenic acid to enhance CD8+ T cell-mediated anti-tumor immunity through an innovated mechanism promoting T cell activation, infiltration, and survival while reducing exhaustion markers The Unmet…
Technology Senolytic Therapeutics To Eliminate Senescent Cells And Enhance Aging And Cancer Treatments Targeted approach to remove aging, disease-related, or chemotherapy/immunotherapy-induced senescent cells while sparing healthy cells The Unmet Need: Approaches to selectively eliminate senescent cells improving aging symptoms without damaging healthy…
Technology Ligand-Directed Photo-Proximity Labeling Technology For Profiling And Detecting Cancer Biomarker Interactions In Live Cells Light-activated chemical probes to label and identify proteins near cancer biomarkers on live cells and tissues, enabling detailed study of protein interactions and signaling pathways relevant to cancer diagnosis and…
News Meet the Teams Selected to Participate in the 2022 Edward L. Kaplan, ’71, New Venture Challenge The Polsky Center for Entrepreneurship and Innovation is pleased to announce the 30 teams selected to participate in Phase II of the 2022 Edward L. Kaplan, ’71, New Venture Challenge...
