News OrisDX Wins 2022 Edward L. Kaplan, ’71, New Venture Challenge with Saliva Test to Diagnose Oral Cancers UPDATE: The investment totals have been updated to reflect additional investment made in the days following the winner announcement. A startup developing saliva-based diagnostics to screen for oral cancers and...
Technology Antibody-Polymer Conjugates For Engaging T Cells To Destroy Cancer Cells An antibody linked to a polymer that connects T cells to cancer cells enabling broad cancer targeting and effective tumor cell killing without needing tumor-specific antigens The Unmet Need: Novel…
Technology Automated Microfluidic Platform For High-Throughput 3D Cell Culture, Dynamic Stimulation, And Single-Cell Analysis Automated microfluidic platform enabling high-throughput, precise 3D cell and organoid culture, drug screening, and single-cell analysis, allowing real-time monitoring and dynamic control of cellular environments for advanced research in cancer,…
Technology Type I Interferons For Enhancing Chimeric Antigen Receptor T-Cell Efficacy Method to enhance CAR T-cell efficacy by incorporating low-dose exogenous IFN-α2 into CD19-directed, CD28-costimulated CAR T cells post-transduction during manufacturing boosting cytolytic molecule expression, cytokine secretion, and cytotoxicity while minimizing…
Technology Small Molecule Therapeutics For Inhibiting Carotid Body Hypersensitivity To Treat Sleep-Related Breathing Disorders New compounds that inhibit an enzyme to reduce hydrogen sulfide in the carotid body, helping to normalize breathing and prevent sleep apnea by targeting the underlying cause of abnormal breathing…
Technology Pan-Specific γ9δ2 T-Cell Antibodies For Activation And Targeted Cancer Immunotherapy A panel of pan-specific Vγ9Vδ2 TCR-recognizing antibodies that allosterically trigger T-cell activation to engage and kill cancer cells, making it highly applicable for targeted cancer therapy. The Unmet Need: Strategy…
News Meet the Resurgence Cohort 1 Startups: Alpha Nur Team Members Kevin O’Sullivan – Cofounder and CEO What does your company do? Alpha Nur is pioneering nuclear fuel recycling technologies to bolster American national security and clean energy development...
Page Health & Life Sciences Novel treatments, medical devices, diagnostics, and research tools spanning a range of therapeutic areas.
Technology Probing Cellular Activity Via Charge-Sensitive Quantum Nanoprobes Quantum nanoprobe system enables real-time probing of intracellular chemical environments and activity to advance biological and medical diagnostics The Unmet Need: Novel ways to probe cellular processes and improve biological…
News Multi-Tissue Organoid Better Predicts Human Response to Drug Treatments: CellCipher CellCipher has developed a new type of organoid model that captures nearly 70 different cell types to enable drug discovery and personalized medicine. In vitro human models, including organoids and...
News Storing Renewable Energy Generating electrical power from the sun and the wind share a common drawback: The sun does not always shine and the wind does not always blow when and where the...
Technology Novel Use of a Bet Bromodomain Protein Inhibitor (JQ1) for the Treatment of Sickle Cell Anemia and Thalassemia Embryonic and fetal hemoglobin have a higher affinity for oxygen than their adult counterpart, and as such, gene editing techniques to revert red blood cells to produce infant or fetal…
