News University of Chicago Announces Partnership with AI Research Commons, Microsoft, and NVIDIA to Accelerate Midwest AI Startups Inception-stage startups to receive Microsoft for Startups’ technical and go-to-market support, up to $350K in Startup credits on eligible services, and AI model access; benefits from the NVIDIA Inception program for...
Page License Technologies technology Licensing Discover new solutions to expand your pipeline with breakthrough, validated technologies ready for commercialization. Technologies at the University of Chicago are available for licensing across several industries, from...
Technology A Spatially Resolved Intracellular Photoproximity Profiling Technology For Mapping And Targeting Protein Interactions In Cancer A matched pair of photoproximity probes coupled with quantitative proteomics which enable context-dependent mapping of protein complex topology inside cells including to map MYC interactomes across temporal, spatial and disease-relevant…
Technology Peripherally Restricted Κ-Opioid Receptor Agonist Co-Formulation For Preventing Opioid-Induced Respiratory Depression An opioid painkiller combined with a peripherally restricted κ-opioid receptor agonist stimulating the carotid body to prevent opioid-induced respiratory depression, enhancing breathing without affecting pain relief or causing central side…
Technology New Antibiotics and Antibiotic Potentiators for Treating Staphylococcus Aureus Infections Methicillin-resistant Staphylococcus aureus (MRSA) infection is the leading cause of skin and soft tissue infections that affect nearly 30% of healthy adults. Staph infections can escalate in intensity if introduced to…
Technology An Engineered Hypercompact CRISPR-Cas12f System with Boosted Gene-Editing Activity The engineered hypercompact enAsCas12f system addresses CRISPR-Cas systems deliverability issues while offering enhanced gene-editing high specificity making it ideal for therapeutic applications using AAV delivery. The unmet Need: New CRISPR-systems…
Technology A High-Throughput, Label-Free Microfluidic System For Combinatorial Droplet Generation, Storage, And Analysis A microfluidic platform consisting of a two-layer PDMS system that generates and stores combinatorial droplets, enabling high-throughput screening with an integrated label-free, image-based detection system for real-time quantification of droplet…
Technology A Computational And Therapeutic Platform For Identifying And Correcting Unproductive Splicing To Restore Gene Expression Advanced computational tools to identify faulty RNA splicing events and design of antisense oligonucleotides to restore normal protein production in genetic diseases, especially those affecting the brain The Unmet Need:…
Technology Enhanced Vaccine Efficiency via an Antigen Targeting, Immune Stimulating Co-polymer Vaccine efficacy is limited due to the inability to deliver in-tact antigens to antigen presenting (APC) dendritic cells (DCs) while simultaneously activating the cells in a non-toxic fashion. Adjuvants have…
Technology A Prognostic Gene Signature for Predicting Chemotherapy Sensitivity and Patient Survival in ER-negative Breast Cancer ER-negative (ER-) breast cancers make up 20% of all breast cancer diagnosis. However, no gene signature exists for predicting drug sensitivity and prognosis. Therefore, the clinical standard remains treating patients…
Technology Method of Growth Factor Delivery for Accelerated Wound Healing Appearance of ulcers and slow wound healing are a hallmark symptom of several autoimmune disorders including type II diabetes. Current treatment approaches rely on antiquated bandaging, however bulkiness and inconvenience…
Technology SCALES: A System For Predicting Interaction And Function In Bacteria Using Co-Variation The current understanding of how proteins interact to create collective functional groups (e.g., complexes, pathways, meta-pathways) is incomplete and difficult to elucidate. Therefore, the current methods used to characterize/identify the…
