Technology Ketone Carbonyl Atom Swap Platform For Drug Discovery And Lead Optimization A two-step chemical process using a special reagent to swap a ketone's oxygen atom with a sulfur atom creating new compounds, particularly useful for making improved drugs The Unmet Need:…
Technology Prophylactic Strategy For C. Difficile Infection Prevention This technology is a prevention method for those at risk of C. difficile infection using a mutated strain of C. difficile that reduces toxicity and competes with virulent strains, offering…
News Polsky Supports 13 Teams in Spring Quarter I-Corps Cohort The Polsky Center ran its National Science Foundation (NSF)-supported I-Corps program virtually during the Spring quarter and accepted the largest number of teams of any cohort managed to-date. Polsky supported...
Technology Boosting Cancer Immunotherapy Or Radio-Immunotherapy For Enhanced Tumor Eradication New cancer therapy to enhance the efficacy of checkpoint inhibitor immunotherapy and radiation by blocking tumor-promoting signals from erythroid progenitor cells, which secrete artemin to advance cancer progression. This approach…
News 22 Teams From Across Campus Explore Commercial Potential of New Ideas More than 20 teams participated in the Polsky Center I-Corps program this academic year – all with new research and ideas addressing challenges across various industries. The goal of the...
Technology In Vitro Assay To Select Optimal Small RNA Guides To Redirect ADAR (Adenosine Deaminase That Acts On RNA) Enzymes A breakthrough method to systematically select for optimal small guide RNAs using an unbiased approach for improved accuracy and efficiency of all systems of site-directed RNA editing. The Unmet Need:…
News PODU, the First Arabic Podcast Platform, Wins $15,000 at the 2019 College New Venture Challenge The Polsky Center for Entrepreneurship and Innovation at the University of Chicago is pleased to announce the winners of the 2019 College New Venture Challenge (CNVC).
News 21 Teams Tackling Innovations in Quantum, Healthcare, AI, and More Take First Steps Toward Commercialization Twenty-one teams from across the University of Chicago and local institutions participated in the Polsky Center I-Corps program this year – identifying and addressing real-world problems in seven weeks, work...
Technology Improved Ex Vivo Models Of Pancreatic Cancer Using Tumor-Relevant Nutrient Conditions Tumor Interstitial Fluid Medium (TIFM) is a pancreatic tumor-mimetic cell culture formulation, paired with matched murine PDAC cell lines adapted in either TIFM or RPMI-1640, that is designed to model…
Program Course Information The PE/VC Lab course equips students with timely practical tools and imparts insights from industry veterans with the ultimate goal of accelerating the apprenticeship process for those aspiring to work...
Technology Improved Photovoltaic Materials Based on Alpha-Substituted Perylene Diimide Use of organic photovoltaic (OPV) solar cells are a developing energy technology which shows significant potential to become a cheap source of electric energy production even when compared to silicon-based…