Technology Boosting Cancer Immunotherapy Or Radio-Immunotherapy For Enhanced Tumor Eradication New cancer therapy to enhance the efficacy of checkpoint inhibitor immunotherapy and radiation by blocking tumor-promoting signals from erythroid progenitor cells, which secrete artemin to advance cancer progression. This approach…
Page Health & Life Sciences Novel treatments, medical devices, diagnostics, and research tools spanning a range of therapeutic areas.
Technology Nanoscale Metal-Organic Frameworks For X-Ray Triggered Combination Cancer Therapy A nanoscale metal-organic framework uses heavy metals to enhance X-ray absorption, triggering prodrug activation for precise cancer treatment by combining radiotherapy, chemotherapy, and immunotherapy with reduced systemic toxicity. The Unmet…
Technology Targeting TGFβ Signaling for Enhancing Cancer Radiotherapy and Immunotherapy Efficacy The method leverages a negative regulator to inhibit TGFβ signaling in myeloid cells, potentially enhancing the efficacy of radiotherapy and immunotherapy in cancer treatment by reducing immune suppression. The problem:…
Technology Amphiregulin Screening And Inhibition Methods For Reducing Metastasis And Enhancing Radiotherapy Efficacy Methods to improve radiotherapy by blocking the protein Amphiregulin (AREG), which helps tumors resist treatment and spread. Inhibiting AREG enhances anti-tumor effects and reduces metastasis, making radiotherapy more effective …
Technology IRDS: Predictive 7-gene Signature for Breast Cancer Therapy After surgical removal of breast cancer tumors, adjuvant chemotherapy and radiation therapy have an absolute survival benefit of just 5-10%. Currently approved breast cancer diagnostics do not predict patient responses…
Technology Tumor Aneuploidy Score As A Predictor Of Immunotherapy Response Tumor aneuploidy scoring delivers improved immunotherapy response prediction, enhancing personalized cancer treatment by providing prognostic insights beyond existing biomarkers like tumor mutational burden. The Unmet Need: Reliable biomarkers to predict immunotherapy…
Technology siRNA/shRNA Therapy for the Sensitization of Treatment-resistant Solid Tumors to Chemo and Radiation Therapy Adjuvant radiation therapy post-surgery remains largely ineffective, with just 5% of patients showing a survival benefit. Small molecule JAK inhibitors have shown efficacy in the clinic at treating these patients,…
Technology Targeting the BRCA1 Pseudogene (BRCA1P1) to Inhibit Cancer Progression and Increase Therapy Responses Compositions and methods to target long non-coding RNA (lncRNA) from the BRCA1 pseudogene in breast cancer cells to stimulate the body’s natural immune response, leading to increased cancer cell death…
Technology A Gene-Modified T Cell Platform For Spatially Controlled Therapeutic Protein Delivery In Response To Radiation Engineered T cells to release cancer-killing proteins only when activated by targeted radiation, enabling precise, localized tumor treatment while minimizing side effects and improving the effectiveness of CAR-T therapy for…
News Novel Breast Cancer Therapy Shows Promise Moving a basic scientific finding from a lab to the clinical setting is the Holy Grail for medical researchers the world over. Suzanne Conzen, MD, professor of hematology/oncology at the...
