Technology UV Disinfecting System to Facilitate N95 Respirator Re-Use Currently there are several solutions under consideration for disinfecting N95 respirators for re-use, with UV-C as the preferred solution because of ease of deployment and widespread applicability. Problematically, present UV-C…
Technology Wearable Microelectromechanical Sensing System For Integrated Respiratory And Physiological Signal Monitoring A wearable, wireless sensor that integrates flexible, capacitive, acoustic, and optical technologies to continuously monitor breathing, heart signals, and oxygen levels for accurate sleep apnea and respiratory condition diagnosis. The…
Technology Improved Electrochemical Li Extraction From Seawater And Other Dilute Li Sources Using Mixed Li An Na Layered Oxides Use of Li in electric vehicle batteries, portable electronic devices, and stationary energy storage applications has expanded significantly in recent years, and this growth is expected to continue to increase. …
Technology Optogenetic Protein Fusion for Precise And Low-Impact Actin Cytoskeleton Imaging In Cells A light-sensitive version of LifeAct, a peptide used to label actin in cells, to reduce its harmful side effects by controlling its binding through light exposure, improving cell imaging and…
Technology Prophylactic Strategy For C. Difficile Infection Prevention This technology is a prevention method for those at risk of C. difficile infection using a mutated strain of C. difficile that reduces toxicity and competes with virulent strains, offering…
Technology RNA Editing Technology for Enhancing Tumor Immunogenicity and Immune Checkpoint Inhibitors Novel RNA editing method to generate a multitude of neoantigens in tumor cells making the cells more recognizable by T cells and enhancing the efficacy of immune checkpoint inhibitors The…
Technology Engineered Flt3L Variants For Antigen Tolerance Induction Engineered recombinant fusion of the dendritic cell growth factor Flt3L to serum albumin to modulate the antigen-presenting compartment and bias it toward tolerance particularly against therapeutic proteins. The Unmet Need:…
Technology Bioadhesive Polymer for Connecting Semiconductors to Wet Tissue This method imparts bioadhesive properties onto polymeric semiconductors, which enables effective transductions of bio-signals from biological tissues to electronic devices. The Unmet Need: Conformable and stable integration of semiconductor-based biosensing…
Technology Minimally Invasive System To Deliver, Retain Drugs In The Kidney This device provides minimally invasive drug delivery and retention to the inside of the kidney The Unmet Need: This device provides minimally invasive drug delivery and retention to the…
Technology Data-Driven Discovery Of Innate Immunomodulators Via Machine Learning-Guided High Throughput Screening Novel machine learning-enable platform to guide in vitro experimental screening and discovery of small molecule immunomodulators to improve immune responses The unmet need: Platform to resolve unregulated immune potentiator…
Technology Ligand-Directed Photo-Proximity Labeling Technology For Profiling And Detecting Cancer Biomarker Interactions In Live Cells Light-activated chemical probes to label and identify proteins near cancer biomarkers on live cells and tissues, enabling detailed study of protein interactions and signaling pathways relevant to cancer diagnosis and…
Technology Reversible Gene Editing System For Site-Specific Large DNA Integration And Excision The Unmet Need: Methods for efficient, reversible integration and excision of large DNA Genome engineering is a rapidly advancing field with immense potential for synthetic biology and gene therapy. The…
