Technology Novel Mycobacterial Small Molecules That Bind MR1 And Are Activating Or Antagonistic For MR1-Restricted T cells. TB bacterium, Mycobacterium tuberculosis (M. tuberculosis), is extremely slow growing compared to other bacteria and is naturally resistant to many of the powerful antibiotics that are effective against other bacterial…
Technology CAR T-Cells That Recognize Cancer-specific Glycopeptides Across Multiple Cancer Types The development of cancer immunotherapies is limited by a lack of targetable tumor antigens. Most currently targeted antigens have basal expression in healthy tissue, which results in potentially life threatening…
Technology Novel Small Molecules For Treatment Of Breast and Ovarian Cancer According to the National Osteoporosis Foundation (NOF) approximately 10.2 million adults in the United States have osteoporosis, with an additional 43.4 million having low bone mass. One in eight women…
Technology Development Of A Novel Anti-fibrotic (siRNA Talin2) That Reverses Existing Fibrosis Fibrosis is involved in 45% of deaths in the United States, and no treatment exists to reverse the progression of the disease. Fibrosing diseases include pulmonary fibrosis, congestive heart failure,…
Technology DeMaND (Decoding using Manifold Neural Dynamics) This method enables high fidelity decoding of neural activity in an interpretable manner with a small training data set. The Unmet Need: Measuring neural activity in the brain with a…
Technology Point Of Care Monitoring Of Inflammatory Diseases A quantitative method of calprotectin measurement from various biological samples to monitor disease severity, progression, and effectiveness of treatment interventions in inflammatory diseases. The Unmet Need: A simple and quantitative…
Program Our Process and Advisory Committee Program Structure The George Shultz Innovation Fund runs once a year in the Spring quarter. Our process is a hybrid: it pairs a hands-on readiness sprint with the rigorous due...
News The Polsky Center to Support Quantum Ecosystem as Part of $55M Bloch Quantum Tech Hub Initiative The Polsky Center for Entrepreneurship and Innovation will provide resources to help quantum companies grow as part of a new $55 million effort to build a domestic quantum supply chain...
Program Past Participants 2025 Folasade Rancie – Doulala Michael Gustafson – Three Pillars Sudanshu Kaushik – Exalt Data Randel Bennett – Qixent Laurel Alpaugh – Coclo Ritu Sreenivasan – Mooj Foods Shikhar Pandey…
News Polsky 10: Polsky Center partners with Current | Scaffold raises $15M | From pre-seed to Series C The Polsky 10 is a bi-weekly newsletter featuring 10 things to know from the University of Chicago’s Polsky Center. To get the Polsky 10 sent directly to your inbox every...
