News Improving Crops; Saving Energy On August 20, Chromatin—a company that grew out of research at the University of Chicago—announced that it had entered into a technological alliance and license agreement with Bayer CropScience. Under the agreement, Bayer...
Technology RNA Methylation Depletion To Induce Transcriptional Repression For Effective Leukemia Treatment A novel mechanism for 5-azacytidine-mediated depletion of RNA 5-methylcytosine on chromatin-associated RNA leading to global transcriptional repression through two epigenetic pathways enabling more precise and effective leukemia treatments The Unmet…
News Fostering a New Entrepreneurial Spirit As an Executive-in-Residence at UChicagoTech, Joseph Feldman has had many “aha” moments helping to build a more entrepreneurial spirit at the University. One came last year when Feldman and others...
Technology A Spatially Resolved Intracellular Photoproximity Profiling Technology For Mapping And Targeting Protein Interactions In Cancer A matched pair of photoproximity probes coupled with quantitative proteomics which enable context-dependent mapping of protein complex topology inside cells including to map MYC interactomes across temporal, spatial and disease-relevant…
Technology Small Molecule Inhibitors Targeting RNA Modifying Enzymes to Modulate Drug Response and Overcome Drug Resistance DNA hypomethylating agents have been widely used to treat various hematologic and non-hematologic malignancies. However, accumulating evidence has demonstrated that DNA methylation status does not correlate with clinical response to…
News This is How Women are Really Faring in Chicago Tech Amanda Lannert belongs to an exclusive club. Along with Kristi Ross of online investment company Tastytrade and Daphne Preuss of bio-agriculture company Chromatin, she is among a trio of female...
News Absolute Antibody Partners with the Recombinant Antibody Network to Facilitate Access to Engineered Recombinant Antibodies Absolute Antibody Ltd., an industry-leading provider of recombinant antibody products and services, has announced a partnership with the Recombinant Antibody Network (RAN), a consortium of three expert centers at the...