News 22 Teams From Across Campus Explore Commercial Potential of New Ideas More than 20 teams participated in the Polsky Center I-Corps program this academic year – all with new research and ideas addressing challenges across various industries. The goal of the...
News ‘It’s Remarkable’: Deep Tech Ventures Summit Showcases Innovation in the Midwest Nearly 350 attendees, 23 speakers, and 22 startups came together to explore various topics across the quantum, data science and AI, cleantech, and life sciences space at the Deep Tech...
News 16 UChicago Researchers Awarded $7.2 Million from Chan Zuckerberg Biohub Chicago The Chan Zuckerberg Biohub Chicago has funded its first cohort of Investigators at its partner institutions – including 16 researchers from the University of Chicago. The funding – a total...
News George Shultz Innovation Fund Announces 4 Finalists Pitching for Potential Investment The 2026 George Shultz Innovation Fund finalists are developing novel software, medical devices, and therapeutics. Managed by the Polsky Center for Entrepreneurship and Innovation, the George Shultz Innovation Fund provides up to...
Technology Peripherally Restricted Κ-Opioid Receptor Agonist Co-Formulation For Preventing Opioid-Induced Respiratory Depression An opioid painkiller combined with a peripherally restricted κ-opioid receptor agonist stimulating the carotid body to prevent opioid-induced respiratory depression, enhancing breathing without affecting pain relief or causing central side…
Technology Deep Learning Uncertainty Quantification System For Reliable Cancer Histopathology Diagnosis Deep learning and uncertainty estimation (via Monte Carlo dropout and cross-validation) to classify digital pathology images by confidence, improving reliability in cancer diagnostics and supporting effective clinical decision-making The Unmet…
Technology Protein Engineering Strategy for Enhancing Healing Of Chronic Diabetic and Radiation-Induced Wounds The problem: Chronic, non‐healing wounds have reached epidemic proportions and have a sustainable impact on both an individual’s quality of life and on healthcare costs as a whole The field…
Technology A Highly-Efficient Platform To Form Vesicular Polymer Nanoparticles For RNA And Protein Payload Delivery Polymersomes are a type of nanoscale vesicle made from block copolymers and can encapsulate a variety of therapeutic agents including proteins and nucleic acids. These nanovesicles are assembled at room…
Technology CD200-Antigen Fusion Proteins For Myeloid-Targeted Antigen-Specific Immune Tolerance CD200-antigen fusion proteins target myeloid cells to deliver inhibitory CD200R signals, enhancing antigen uptake and presentation while dampening inflammation to induce antigen-specific immune tolerance The Unmet Need: Antigen-specific therapies for…
Technology Novel Mycobacterial Small Molecules That Bind MR1 And Are Activating Or Antagonistic For MR1-Restricted T cells. TB bacterium, Mycobacterium tuberculosis (M. tuberculosis), is extremely slow growing compared to other bacteria and is naturally resistant to many of the powerful antibiotics that are effective against other bacterial…
Technology A Method for Fast Adapting Similarity Searches Based on Variance Aware Quantization With the explosive growth of high-dimensional data, approximate methods emerge as promising solutions for searching for similar data pairs. Quantization methods have gained prominence due to their low storage costs…
Technology Fully Synthetic Adjuvant Delivery System For Enhanced Tumor-Targeted Immunotherapy A cancer vaccine that enhances immune response by directly binding adjuvants to tumor cells, avoiding targeting antibodies, and reducing related side effects The problem: Therapeutic vaccination has long been a…