Technology Ligand-Directed Photo-Proximity Labeling Technology For Profiling And Detecting Cancer Biomarker Interactions In Live Cells Light-activated chemical probes to label and identify proteins near cancer biomarkers on live cells and tissues, enabling detailed study of protein interactions and signaling pathways relevant to cancer diagnosis and…
Technology A Gene-Modified T Cell Platform For Spatially Controlled Therapeutic Protein Delivery In Response To Radiation Engineered T cells to release cancer-killing proteins only when activated by targeted radiation, enabling precise, localized tumor treatment while minimizing side effects and improving the effectiveness of CAR-T therapy for…
Technology AI-Enhanced Single-Photon Quantum Detectors This technology uses advanced machine learning algorithms to extract significantly more information from single-photon detector signals than conventional approaches. By analyzing full detector waveforms in real time, the technology improves…
Technology Amphiregulin Screening And Inhibition Methods For Reducing Metastasis And Enhancing Radiotherapy Efficacy Methods to improve radiotherapy by blocking the protein Amphiregulin (AREG), which helps tumors resist treatment and spread. Inhibiting AREG enhances anti-tumor effects and reduces metastasis, making radiotherapy more effective …
Technology A Next-Generation mRNA Vaccine Platform For Enhancing T-Cell Responses And Improving Antiviral And Antitumor Immunity Next-generation mRNA vaccine platform uses a lipid-polymer hybrid nanoparticle to boost stability, immune cell uptake, and T cell responses, leading to stronger and longer-lasting protection against viruses and cancer while…
Page About Us about us Advancing innovative ideas and technologies from the University of Chicago ecosystem to the world. The Polsky Center’s roots trace back to the University of Chicago’s longstanding commitment to...
Technology Palm-Free Haptics: Full-Hand Touch Feedback for VR/AR and Wearable Interfaces Summary University of Chicago researchers have developed a wearable electro-tactile feedback technique that creates touch sensations across the palm and fingers without placing electrodes directly on the palm. By positioning…
Technology Rapid Selection Of High-Value Internalizing Binders For Targeted Therapeutics Lentiviral display platform engineered to directly select and enrich antibodies based on their ability to induce receptor-mediated endocytosis, thereby streamlining the discovery of highly internalizing candidates for targeted therapies The…
Technology Real-Time High-Definition Mapping Platform For Complex Cardiac Arrhythmia Intervention A novel high-resolution mapping platform offering real-time blockline angle, crossing point analytics, and fiber orientation visualization to enable targeted arrhythmia intervention and improved ablation outcomes. The Unmet Need: Current mapping…
Technology Ultrathin, Plasmonic Schottky Biointerfaces For Wireless Stimulation And Sensing A plasmon-enhanced hierarchical gold–titania (Au-TiO₂) Schottky junction biointerface designed for wireless, energy-efficient biological stimulation (neuromodulation, cardiac pacing), real-time biosensing, and minimally invasive artificial vision. The platform is scalable, CMOS-free, and…
Technology Spectral CT Material Decomposition from Standard Single-Energy X-Ray Scans Summary This technology enables multi-material image reconstruction from conventional single-spectrum X-ray tomography data, including standard CT and tomosynthesis, without requiring dual-energy CT or photon-counting CT hardware. The approach can generate…
Technology Next-Generation Minimally Invasive Optoelectronic Implants For Chronic Disease Management The platform delivers ultra-low intensity, wireless, fully implantable photostimulation for deep tissue targets (nerves, heart, diaphragm). It spatially separates light harvesting from bioelectrical stimulation, enabling minimally invasive, leadless, genetic-modification-free interventions.…
